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Meperidine is also known as Demerol, pethidine. This is a class of  Synthetic, Opioids; Opioid Analgesics. is a pain reliever. It is used to treat moderate to severe pain.

DESCRIPTION
DEMEROL (meperidine hydrochloride, USP) Tablet and Oral Solution these are opioid agonists. DEMEROL Tablets is available as 50 mg and 100 mg Tablets for oral administration. We also have available other forms of demerol like DEMEROL HCL INJECTION USP . The chemical name is 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-,ethyl ester, hydrochloride. The molecular weight is 283,80. Its molecular formula is C15H21NO2· HCl, and it has the following chemical structure.

DEMEROL® (meperidine hydrochloride) Structural Formula Illustration
Meperidine hydrochloride is a white crystalline substance with a melting point of 186°C to 189°C. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling.

The Tablets contain 50 mg or 100 mg of meperidine hydrochloride.

The DEMEROL Oral Solution is a pleasant-tasting, nonalcoholic, banana-flavored solution containing 50 mg of meperidine hydrochloride, per 5 mL (10 mg/mL).

Meperidine contain some Inactive Ingredients these include: Calcium Sulfate, Dibasic Calcium Phosphate, Starch, Stearic Acid, and Talc. The Tablets are white, round and convex. The 50 mg is a scored tablet and has a stylized “W” on one side and “D” over “35” on the other side. The 100 mg is a scored tablet and has a stylized “W” on one side and “D” over “37” on the other side.

The Inactive Ingredients in DEMEROL Oral Solution include: Benzoic Acid, Flavor, Liquid Glucose, Purified Water, Saccharin Sodium.


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Initial Dosage
Adults
Initiate treatment with DEMEROL Tablets or Oral Solution in a dosing range of 50 mg to 150 mg orally, every 3 or 4 hours as needed for pain.

Pediatric Patients
Initiate treatment with DEMEROL Tablets or Oral Solution in a dosing range of 1.1 mg/kg to 1.8 mg/kg orally, up to the adult dose, every 3 or 4 hours as necessary


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