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Common street names: Thang, Krypton, Kakuam, Thom, Ketum, Biak-Biak.
A painkiller with just one of these properties increasing doses to relieve the same amount of pain. would be great, but we
thinks we have stumbled onto a class of chemicals that might have them all. They are found in kratom,

What is Kratom? Buy Kratom online
Kratom (Mitragyna speciosa) is a tropical evergreen tree from Southeast Asia and is native to Thailand, Malaysia,
Indonesia and Papua New Guinea. Kratom, the original name used in Thailand, is a member of the Rubiaceae family.
Other members of the Rubiaceae family include coffee and gardenia.

How to use Kratom
The leaves of kratom are consumed either by chewing, or by drying and smoking, putting into capsules, tablets or extract,
or by boiling into a tea. The effects are unique in that stimulation occurs at low doses and opioid-like depressant and
euphoric effects occur at higher doses.

Uses
Kratom has become popular as a recreational drug and can improve mood, relieve pain and help with to help prevent
withdrawal from opiates (such as prescription narcotics or heroin), and for mild stimulation increasing doses to relieve the
same amount of pain.

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Kratom Doses

At lower range, roughly 1 to 5 grams of the leaves, it is said to produce mild stimulant effects or anxiety, while higher doses of
about (5 to 15 grams) produce euphoria effects more in-line with opioids. Doses exceeding 15 grams can lead to a state of
excessive sedation and stupor the best so far. Effects can vary from person to person, and a reaction from a low dose or high
dose may not be the same in all people.

While some people may use kratom for recreational use, others may be using it for pain relief or opioid withdrawal. However, it
is important to note that these anecdotal doses have not been substantiated or shown in clinical trials to be safe or effective.

Kratom Effects and Actions
Most of the psychoactive effects of kratom have evolved from anecdotal and case reports. Kratom has an unusual action of
producing both stimulant effects at lower doses and more CNS depressant side effects at higher doses. Stimulant effects
manifest as increased alertness, boosted physical energy, talkativeness, and a more social behavior. At higher doses, the
opioid and CNS depressant effects predominate.

Kratom's Effects at Low Doses
At a low dose (1-5 g) of kratom, stimulant-like effects predominate. These are felt within reportedly beginning within 10
minutes after consumption and lasting from one to five hours.. While reports by users indicate that most people find these
effects pleasant, some users experience an uncomfortable sense of anxiety and agitation. The primary stimulant-like effects
of kratom are similar to amphetamine, though less intense, and include:
Heightened libido.
Sedation.
Nausea.
Sweating.

How Opioid Pain Meds Work in the Brain | Body

A portion of the pain med compound binds to receptors at the injury site. A portion of the pain med compound binds to opioid
receptors found throughout the brain and nervous system - the receptors on neural networks involved with the “complicated”
bit above. And a portion trigger massive releases of dopamine neurotransmitters - the neurotransmitters responsible for the
brain’s pleasure/reward neural networks.

With the surge of dopamine component of an opioid pain medication, the pain is not being “killed,” per se - rather it’s being
overwhelmed by the content, euphoric, satisfied feelings that dopamine neural networks provide. And, of course, the brain
likes that feeling, so it maps the desire for pleasure (which comes with the pain meds), in addition to all of the other brain
mapping going on.
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